Closed Restricted Access Barrier System (cRABS)

Secure your aseptic production and guarantee product safety with a high-performance barrier system that maintains precise, controlled conditions throughout your entire process.

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Designed for controlled aseptic processing.

Protect your pharmaceutical integrity during filling and freeze-drying with unidirectional laminar airflow (UDAF) and physical barrier separation designed for consistent, GMP-compliant results. The cRABS is available in two variants.

Benefits

Safety

Effective product and operator protection

Reduce the risks of contamination and exposure. The cRABS housing with glove access creates a physical barrier between operator and product, making both the product and the operator safe from hazard.

Reduced risks

Controlled aseptic conditions

Ensure your products are processed under controlled aseptic conditions, reducing contamination risks for vials, syringes, cartridges and bags.

Regulations

GMP Compliance

Ensure your production processes meet strict industry standards with a solution designed for aseptic operation and controlled environments.

Customization

Tailored to your needs

Whether you are filling unique syringes or loading a specific type of freeze dryer, the cRABS is customized to fit your operation needs.

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Specialized housing for aseptic processes

The Closed Restricted Access Barrier System (cRABS) serves as a specialized housing for aseptic processes, specifically for the filling, loading, and unloading of freeze dryers.  

This solution prioritizes product safety by establishing a physical barrier between the operator and the materials being processed. Beyond the physical shield, the system maintains a safe and robust environment through a Laminar Air Flow System and precise overpressure control.  

Features & capabilities

Explore the main features of the cRABS solution:

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Variants

Different system variants tailored to your needs 

Depending on your applications, the cRABS can be modified to work for aseptic applications (like PROLine) or toxic/containment applications (like PROcLine). 

Because every system is customized, the specific choice is fitted to your needs and the requirements of your facility.  

This approach ensures that the barrier system provides optimal protection for filling, loading, and unloading of freeze dryers while maintaining the necessary hygienic design standards for your specific application. 

FAQs

Related solutions

Explore other aseptic processing solutions.

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PPI

The Personal Product Isolator provides targeted product protection in aseptic processes with unidirectional laminar airflow.

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PROLine

PROLine provides high-performance, customized isolator systems designed for aseptic processes, such as filling and freeze-dryer loading and unloading.

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PROcLine

A GMP-compliant isolator system for highly potent and toxic pharmaceuticals, delivering validated aseptic containment for safe product and operator protection.

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FLI

The FLI is a flexibly configurable isolator providing Grade A product protection and optional operator protection.

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STI

The STI isolator enables sterility testing under advanced aseptic conditions, with optional containment for toxic substances.

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oRABS

The open Restricted Access Barrier System is designed to support compliant aseptic processing by creating a controlled barrier between operator and product.

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Cellefill & Flexfill

Cellefill & Flexfill combine modular design with integrated isolator technology to ensure different aseptic fill and finish processes.

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Get in touch

Speak to our specialists about our range of flexible, scalable, end-to-end solutions—tailored to you.